Top 5 Synthetic Nicotine Vape Juice Brands

Synthetic nicotine is the latest advancement in the vape world, and many brands have taken up the challenge of leading the industry in next-generation e-liquids. Always keeping up with the latest technological advancements, VaporFi has brought in several, excellent synthetic vape juice and nicotine salt brands that have been tried and tested by our experts. But what is synthetic nicotine? Where does it come from and how is it made? 

What is Synthetic Nicotine?

Nicotine is usually derived from the tobacco plant, and while this may seem like a more “natural” form of nicotine, the process does involve a chemical process that is anything but natural. Synthetic nicotine on the other hand is lab-derived and not extracted from the tobacco plant. There is no chemical difference between the two forms of nicotine. The only difference is that synthetic nicotine is a more pure form of nicotine, since it does not contain the impurities of tobacco.

How are Synthetic Vape Juice and Nic Salts Made?

Synthetic e-liquids are made pretty much the same way as traditional ejuice. There is a PG/VG ratio of about 50% depending on the intention of the vape juice, and this is mixed with nicotine and flavoring. The only difference is the nicotine is synthetic, or non-tobacco nicotine (NTN). Given the molecular similarities between synthetic nicotine and tobacco-derived nicotine, you won’t notice a huge difference in the effectiveness of the nicotine. Rather, you will notice a difference in taste. Synthetic vape juice will have a more distinctive, intense flavor due to the lack of impurities in the synthetic nicotine. 

Get ready for a more satisfying vape session. Explore our picks for the top 5 synthetic e juice brands at VaporFi.

Air Factory

In terms of sheer flavor madness, Air Factory is king. The vast number of delicious and unique nic salt flavors they offer is truly astounding. Want a tropical flavor adventure? Aloha Strawberry and Peach Passion will whisk you away. Want to relive the dessert snacks of your childhood? Indulge your nostalgia with Kookie Krunch. Want to chill out with some cool mint? Their blend is top notch. Dive into the Air Factory collection today!

Sadboy Nicotine Salts

Sadboy is another incredible NTN manufacturer that has gained a tremendous following due to their incredible nic salts. They have managed to combine incredible flavor and smoothness with satisfying awesome nicotine content. From Shamrock Cookie to Apple Pie to Strawberry Jam, Sadboy has a nic salt flavor for everyone…

Let’s say you’re a vaping innovator. You want to boldly blaze your own path to nic salt flavor nirvana. Well, NicTech is here to help you realize your dreams. NicTech offers custom DIY synthetic nicotine salt blends. You can choose up to 3 flavors to combine and perfect your very own NTN blend. You can also customize nicotine level and VG/PG ratio to tweak your vape juice into a masterpiece. Discover more here…


Vapetasia, a renowned name in the vaping industry, has embraced synthetic nicotine e-liquids, reflecting a commitment to innovation and quality. Their synthetic nicotine blends showcase a dedication to delivering an exceptional vaping experience while offering alternatives to traditional nicotine-based products. With a focus on meeting the evolving needs of vapers, Vapetasia's adoption of synthetic nicotine stands as a testament to their dedication to advancing the industry while providing users with diverse and high-quality vaping options.


FRE offers a different synthetic nicotine experience. Their NTN pouches are discreet, satisfying, and extremely convenient. These pouches are made to enjoy and fulfill you in any situation. From Wintergreen to Sweet and more, you’re sure to find the perfect flavor for you… 

So there you have it, the 5 best synthetic nicotine brands. Each offers a unique experience and is the pinnacle of their specific field. As always VaporFi offers the lowest prices in the vaping world. Order everything you need right here!